Tetrahydrofuran → N-[17-(3-chloro-6-methoxyisoquinolin-1-yloxy)-13-methyl-2,14-dioxo-3,13,15-triaza-tricyclo[13.3.0.04,6]octadec-7-ene-4-carbonyl](cyclopropyl) sulfonamide
Reaction equation
[C:39]([c:40]1[nH:41][cH:42][cH:43][n:44]1)([c:45]1[nH:46][cH:47][cH:48][n:49]1)=[O:50].[CH2:58]1[CH2:59][CH2:60][C:61]2=[N:66][CH2:65][CH2:64][CH2:63][N:62]2[CH2:67][CH2:68]1.[CH2:69]1[O:70][CH2:71][CH2:72][CH2:73]1.[CH:51]1([S:54](=[O:55])(=[O:56])[NH2:57])[CH2:52][CH2:53]1.[Cl:1][c:2]1[n:3][c:4]([O:14][CH:15]2[CH2:16][N:17]3[C:18](=[O:38])[N:19]([CH3:37])[CH2:20][CH2:21][CH2:22][CH2:23][CH:24]=[CH:25][CH:26]4[CH2:27][C:28]4([C:34](=[O:35])[OH:36])[NH:29][C:30](=[O:33])[CH:31]3[CH2:32]2)[c:5]2[cH:6][cH:7][c:8]([O:12][CH3:13])[cH:9][c:10]2[cH:11]1>>[Cl:1][c:2]1[n:3][c:4]([O:14][CH:15]2[CH2:16][N:17]3[C:18](=[O:38])[N:19]([CH3:37])[CH2:20][CH2:21][CH2:22][CH2:23][CH:24]=[CH:25][CH:26]4[CH2:27][C:28]4([C:34](=[O:36])[NH:57][S:54]([CH:51]4[CH2:52][CH2:53]4)(=[O:55])=[O:56])[NH:29][C:30](=[O:33])[CH:31]3[CH2:32]2)[c:5]2[cH:6][cH:7][c:8]([O:12][CH3:13])[cH:9][c:10]2[cH:11]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-3f7f7aab2c8a458eb5a66c8b5ad9df40
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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