反应详情

A mixture of 1-methyl-1H-indole-6-carboxylic acid methyl ester (3.2 g, 16.1 mmol), hydrazine monohydrate (8.5 g, 169 mmol) and methanol (50 ml) was stirred reflux for 15 h. The mixture was evaporated, water was added and the product was isolated by extraction with chloroform, followed by evaporation.

1. temperaturereflux for 15 h
2. customThe mixture was evaporated
3. additionwater was added
4. customthe product was isolated by extraction with chloroform
5. customfollowed by evaporation