Tetrahydrofurfuryl alcohol → HCID 70655756, compound

HRID 1624213Notes

Reaction equation

HRID 1624213 reaction equation
[Na].[CH2:2]([OH:8])[CH:3]1[O:7][CH2:6][CH2:5][CH2:4]1.Cl[CH2:10][Si:11]([CH3:18])([O:15][CH2:16][CH3:17])[O:12][CH2:13][CH3:14]>[I-].[K+].C1(C)C=CC=CC=1>[CH2:2]([O:8][CH2:10][Si:11]([CH3:18])([O:15][CH2:16][CH3:17])[O:12][CH2:13][CH3:14])[CH:3]1[O:7][CH2:6][CH2:5][CH2:4]1

Participants

6

Reactant 3

HCID 7360Tetrahydrofurfuryl alcoholHCID 16650(Chloromethyl)(diethoxy)methylsilaneHCID 5360545Sodium

Product 1

HCID 70655756HCID 70655756, compound

Reagents, catalysts & solvents 2

HCID 4875Potassium IodideCatalystHCID 1140TolueneSolvent

Procedure

Under conditions similar to Example 3, the reaction product of sodium metal and tetrahydrofurfuryl alcohol was reacted with chloromethylmethyldiethoxysilane in the presence of potassium iodide catalyst in toluene. The reaction proceeded to the desired product only to the extent of 20% with the formation of significant amounts of byproducts.

Sources & evidence

ORD record
ord-a65827bac08f4779b3dc75503d42a238
Source dataset
uspto-grants-2014_07
Patent number
US08779080B2

Reaction notes

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