Benzenesulfonamide, N,4-dimethyl- → HCID 60018874, compound

HRID 1625656Notes

Reaction equation

HRID 1625656 reaction equation
[CH3:1][C:2]1[CH:7]=[CH:6][C:5]([S:8]([NH:11][CH3:12])(=[O:10])=[O:9])=[CH:4][CH:3]=1.[CH2:13]([O:15][C:16](=[O:25])[CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23]Br)[CH3:14].[H-].[Na+]>CN(C=O)C>[CH2:13]([O:15][C:16](=[O:25])[CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][N:11]([CH3:12])[S:8]([C:5]1[CH:6]=[CH:7][C:2]([CH3:1])=[CH:3][CH:4]=1)(=[O:10])=[O:9])[CH3:14]

Participants

5

Reactant 3

HCID 12543Benzenesulfonamide, N,4-dimethyl-HCID 24758Sodium hydrideHCID 264813Ethyl 8-bromooctanoate

Product 1

HCID 60018874HCID 60018874, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

4,N-Dimethylbenzenesulphonamide was reacted with ethyl-8-bromooctanoate in DMF under the influence of sodium hydride to obtain 8-[Methyl-(toluene-4-sulfonyl)-amino]-octanoic acid ethyl ester

Sources & evidence

ORD record
ord-4c3c8ca80e924202bd61c90bc735264a
Source dataset
uspto-grants-2014_07
Patent number
US08785381B2

Reaction notes

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