Tetrahydrofuran → 2-((2-Chloro-6-fluorophenyl)amino)-N-(4-cyclopropylphenyl)-1,7,7-trimethyl-7,8-dihydro-1H-benzofuro[4,5-d]imidazole-5-carboxamide
Reaction equation
[CH2:51]1[O:52][CH2:53][CH2:54][CH2:55]1.[CH:32]1([c:35]2[cH:36][cH:37][c:38]([NH2:39])[cH:40][cH:41]2)[CH2:33][CH2:34]1.[CH:42]([N:43]([CH2:44][CH3:45])[CH:46]([CH3:47])[CH3:48])([CH3:49])[CH3:50].[Cl:1][c:2]1[c:3]([NH:9][c:10]2[n:11][c:12]3[c:13]([n:14]2[CH3:15])[c:16]2[c:20]([c:21]([C:23](=[O:24])[OH:25])[cH:22]3)[O:19][C:18]([CH3:26])([CH3:27])[CH2:17]2)[c:4]([F:8])[cH:5][cH:6][cH:7]1.[S:28]([Cl:29])([Cl:30])=[O:31]>>[Cl:1][c:2]1[c:3]([NH:9][c:10]2[n:11][c:12]3[c:13]([n:14]2[CH3:15])[c:16]2[c:20]([c:21]([C:23](=[O:24])[NH:39][c:38]4[cH:37][cH:36][c:35]([CH:32]5[CH2:33][CH2:34]5)[cH:41][cH:40]4)[cH:22]3)[O:19][C:18]([CH3:26])([CH3:27])[CH2:17]2)[c:4]([F:8])[cH:5][cH:6][cH:7]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-75046972724e4c7c8941f9032e544d36
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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