Cyclohexanone Oxime → HCID 57954502, compound

HRID 1630432Notes

Reaction equation

[C:1]1(=[N:7][OH:8])[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.C([O-])(=O)C.C([O-])(=O)C.C([O-])(=O)C.C([O-])(=O)C.[Pb+4].[Cl:26][C:27]([F:32])([F:31])[C:28]([OH:30])=[O:29]>>[Cl:26][C:27]([F:32])([F:31])[C:28]([O:30][C:1]1([N:7]=[O:8])[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1)=[O:29]

Participants

Reactant 3

HCID 7517Cyclohexanone Oxime

HCID 66154Chlorodifluoroacetic acid

HCID 178418268HCID 178418268, compound

Product 1

HCID 57954502HCID 57954502, compound

Procedure

1-Nitrosocyclohexyl 2-chloro-2,2-difluoroacetate was prepared from cyclohexanone oxime, lead tetraacetate and 2-chloro-2,2-difluoroacetic acid using conditions of General Method 3. 1H NMR (250 MHz, chloroform-d) δ 2.13-2.42 (3H, m), 1.79-1.99 (4H, m), 1.51-1.74 (3H, m).

Sources & evidence

ORD record: ord-2cbb99b5679d4b55be3e1c6e63b07f2f
Source dataset: uspto-grants-2014_07
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08791134B2

Reaction notes

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