Trifluoroacetic acid → HCID 57954485, compound

HRID 1630434Notes

Reaction equation

[O:1]1[CH2:6][CH2:5][C:4](=[N:7][OH:8])[CH2:3][CH2:2]1.C([O-])(=O)C.C([O-])(=O)C.C([O-])(=O)C.C([O-])(=O)C.[Pb+4].[F:26][C:27]([F:32])([F:31])[C:28]([OH:30])=[O:29]>>[F:26][C:27]([F:32])([F:31])[C:28]([O:30][C:4]1([N:7]=[O:8])[CH2:5][CH2:6][O:1][CH2:2][CH2:3]1)=[O:29]

Participants

Reactant 3

HCID 6422Trifluoroacetic acid

HCID 12298558N-(oxan-4-ylidene)hydroxylamine

HCID 178418268HCID 178418268, compound

Product 1

HCID 57954485HCID 57954485, compound

Procedure

4-Nitrosotetrahydro-2H-pyran-4-yl 2,2,2-trifluoroacetate was prepared from tetrahydro-pyran-4-one oxime, lead tetraacetate and trifluoroacetic acid using conditions of General Method 3. 1H NMR (250 MHz, chloroform-d) δ 4.18 (2 H, m), 3.75 (2 H, m), 2.53 (2 H, m), 1.92 (2 H, m).

Sources & evidence

ORD record: ord-e40b50d7a02f4cd39008aedd8b2172d1
Source dataset: uspto-grants-2014_07
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08791134B2

Reaction notes

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