HCID 20443325, compound → HCID 13339633, compound

HRID 1632129Notes

Reaction equation

HRID 1632129 reaction equation
[Cl:1][C:2]1[C:3]([C:9](Br)([CH3:15])[CH2:10][C:11]([Cl:14])([Cl:13])[Cl:12])=[N:4][C:5]([Cl:8])=[CH:6][CH:7]=1>C1C=C(Cl)C(Cl)=CC=1.Cl[Cu]>[Cl:1][C:2]1[C:3]([C:9](=[CH2:15])[CH2:10][C:11]([Cl:12])([Cl:14])[Cl:13])=[N:4][C:5]([Cl:8])=[CH:6][CH:7]=1

Participants

4

Reactant 1

HCID 20443325HCID 20443325, compound

Product 1

HCID 13339633HCID 13339633, compoundYield 38%

Reagents, catalysts & solvents 2

HCID 62652Cuprous chlorideCatalystHCID 72391,2-DichlorobenzeneSolvent

Procedure

A slurry of 15 g (0.039 mole) of 3,6-dichloro-2-(1-bromo-3,3,3-trichloro-1-methylpropyl)pyridine and 5 g of finely divided CuCl in O-dichlorobenzene was washed at reflux for two hours. The mixture was cooled, filtered and the filtrate concentrated in vacuo. Recrystallization from pentane yielded 4.5 g (38%) of product, m.p. 71°-74° C.

Workup

  1. temperatureat reflux for two hours
  2. temperatureThe mixture was cooled
  3. filtrationfiltered
  4. concentrationthe filtrate concentrated in vacuo
  5. customRecrystallization from pentane

Sources & evidence

ORD record
ord-177dcd539e17406c8b48b8e268fc3d1e
Source dataset
uspto-grants-1984_10
Patent number
US04474602

Reaction notes

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