Hydrochloric Acid → HCID 13208125, compound

HRID 1632959Notes

Reaction equation

HRID 1632959 reaction equation
Cl.[C:2]1([C:8]2([C:18]([O:20]CC)=O)[CH2:10][CH:9]2[CH2:11][N:12]2[CH2:17][CH2:16][O:15][CH2:14][CH2:13]2)[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[NH:23]1[CH2:27][CH2:26][CH2:25][CH2:24]1>>[C:2]1([C:8]2([C:18]([N:23]3[CH2:27][CH2:26][CH2:25][CH2:24]3)=[O:20])[CH2:10][CH:9]2[CH2:11][N:12]2[CH2:13][CH2:14][O:15][CH2:16][CH2:17]2)[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 31268PyrrolidineHCID 13218423HCID 13218423, compound

Product 1

HCID 13208125HCID 13208125, compound

Procedure

In a manner similar to that described in Example 1, but hydrolyzing the hydrochloride of 1-phenyl 1-ethoxycarbonyl 2-morpholinomethyl cyclopropane (Z) and then treating the intermediate acid chloride with pyrrolidine, there is obtained the product of the formula ##STR15##

Workup

  1. customthere is obtained the product of the formula

Sources & evidence

ORD record
ord-e61d778bb56c43399d76b2f13922786c
Source dataset
uspto-grants-1984_10
Patent number
US04478836

Reaction notes

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