2-Chloroethyl isocyanate → HCID 20441648, compound

HRID 1632965Notes

Reaction equation

HRID 1632965 reaction equation
[Cl:1][C:2]1[CH:3]=[N:4][C:5](=[O:8])[NH:6][CH:7]=1.[Cl:9][CH2:10][CH2:11][N:12]=[C:13]=[O:14]>CN(C)C=O>[Cl:9][CH2:10][CH2:11][NH:12][C:13]([N:4]1[CH:3]=[C:2]([Cl:1])[CH:7]=[N:6][C:5]1=[O:8])=[O:14]

Participants

4

Reactant 2

HCID 160352-Chloroethyl isocyanateHCID 1085785-Chloro-2(1H)-pyrimidinone

Product 1

HCID 20441648HCID 20441648, compoundYield 40%

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

was prepared from 5-chloropyrimidin-2-one and 2-chloroethylisocyanate in dimethyl formamide as described above; yield 40%. 1H NMR (DMSO-d6): δ3.6 (CH2CH2, broad m), 8.41 (2H-4,6), 9.5 (NH).

Sources & evidence

ORD record
ord-c0c07141414549dd840de6b8088f5d0a
Source dataset
uspto-grants-1984_10
Patent number
US04478839

Reaction notes

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