Hydrochloric Acid → HCID 23318282, compound

HRID 1633121Notes

Reaction equation

HRID 1633121 reaction equation
C([NH:4][C:5]1[CH:10]=[C:9]([C:11]([CH3:14])([CH3:13])[CH3:12])[C:8]([O:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH3:31])=[CH:7][C:6]=1[OH:32])(=O)C.[ClH:33]>C(O)C>[ClH:33].[NH2:4][C:5]1[CH:10]=[C:9]([C:11]([CH3:14])([CH3:13])[CH3:12])[C:8]([O:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH3:31])=[CH:7][C:6]=1[OH:32]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 20257269N-[5-tert-Butyl-4-(hexadecyloxy)-2-hydroxyphenyl]acetamide

Product 1

HCID 23318282HCID 23318282, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Conditions

Temperature
80 °C

Procedure

22.4 g (0.05 mol) of 2-acetylamino-4-tert-butyl-5-hexadecyloxyphenol was added to a mixture composed of 50 ml of hydrochloric acid and 150 ml of ethanol and the mixture was stirred with heating at a temperature of 80° C. for 2 hours. after cooling, the crystals deposited were collected by filtration washed with ethanol to obtain 17.9 g of 2-amino-4-tert-butyl-5-hexadecyloxyphenol hydrochloride [1-a].

Workup

  1. temperatureafter cooling
  2. filtrationthe crystals deposited were collected by filtration
  3. washwashed with ethanol

Sources & evidence

ORD record
ord-3cbad78908c942fd8dde4a80a1ab5d4f
Source dataset
uspto-grants-1984_10
Patent number
US04478927

Reaction notes

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