4-Toluenesulfonyl chloride → P-Toluenesulfonylhydrazide

HRID 1633228Notes

Reaction equation

HRID 1633228 reaction equation
NC1C(C=[N:11][NH:12][S:13]([C:16]2[CH:21]=[CH:20][C:19]([CH3:22])=[CH:18][CH:17]=2)(=[O:15])=[O:14])=NC(Cl)=C(Cl)N=1.C1(C)C=CC(S(Cl)(=O)=O)=CC=1.NN>O1CCCC1>[C:19]1([CH3:22])[CH:18]=[CH:17][C:16]([S:13]([NH:12][NH2:11])(=[O:14])=[O:15])=[CH:21][CH:20]=1

Participants

5

Reactant 3

HCID 73974-Toluenesulfonyl chlorideHCID 9321HydrazineHCID 54459351HCID 54459351, compound

Product 1

HCID 15303P-Toluenesulfonylhydrazide

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

p-Toluenesulfonic acid 2-[(3-amino-5,6-dichloropyrazinyl)methylene]hydrazide by the reaction of p-toluenesulfonyl chloride with hydrazine in tetrahydrofuran to form p-toluenesulfonylhydrazine, followed by the reaction of the latter with 3-amino-5,6-dichloropyrazinaldehyde.

Sources & evidence

ORD record
ord-0d21aedb612a4882841e17fa6515729e
Source dataset
uspto-grants-1984_10
Patent number
US04479953

Reaction notes

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