反应详情

5-Aminosalicylic acid (5-ASA), MgO for neutralization, and the additive were mixed in a mortar and made to prepare tablets. The tablets were coated with 11 wt % of a 10 w/v % methanol solution of Eudragit E100 by means of a Hicoater. Then tablets of lactulose were prepared and coated with 11 wt % of a 10 w/v % methanol solution of Eudragit RS100/triacetin (5/1). Each one of the tablets 1 and the tablets 2 and 200 mg of lactose were put in a #1 gelatin capsule. The capsule was coated first with a methanol dispersion of Eudragit RS100L/NaCl (particle size: 75 to 355 μm) (1/2) and then with 12 wt % of Eudragit L100/castor oil (5/1) to obtain the preparation of the present invention.

1. customto prepare tablets