Tetrahydrofuran → 5-Chloro-2-methoxy-4-(methylamino)-N-[2-(1-piperidinyl-methyl)-1-azabicyclo[2.2.2]oct-3-yl]benzamide
Reaction equation
[C:15]([n:16]1[cH:17][cH:18][n:19][cH:20]1)([n:21]1[cH:22][cH:23][n:24][cH:25]1)=[O:26].[Cl:1][c:2]1[c:3]([NH:13][CH3:14])[cH:4][c:5]([O:11][CH3:12])[c:6]([C:7](=[O:8])[OH:9])[cH:10]1.[N:27]1([CH2:33][CH:34]2[N:35]3[CH2:36][CH2:37][CH:38]([CH:39]2[NH2:40])[CH2:41][CH2:42]3)[CH2:28][CH2:29][CH2:30][CH2:31][CH2:32]1.[O:43]1[CH2:44][CH2:45][CH2:46][CH2:47]1>>[Cl:1][c:2]1[c:3]([NH:13][CH3:14])[cH:4][c:5]([O:11][CH3:12])[c:6]([C:7](=[O:9])[NH:40][CH:39]2[CH:34]([CH2:33][N:27]3[CH2:28][CH2:29][CH2:30][CH2:31][CH2:32]3)[N:35]3[CH2:36][CH2:37][CH:38]2[CH2:41][CH2:42]3)[cH:10]1Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-04cb5663a0284862836f4b2bfd7f1275
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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