Phenyl isocyanate → HCID 3297718, compound

HRID 1634797Notes

Reaction equation

HRID 1634797 reaction equation
[CH2:1]([NH2:9])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH3:8].[C:10]1([N:16]=[C:17]=[O:18])[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1>C1COCC1>[CH2:1]([NH:9][C:17]([NH:16][C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1)=[O:18])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH3:8]

Participants

4

Reactant 2

HCID 7672Phenyl isocyanateHCID 8143Octylamine

Product 1

HCID 3297718HCID 3297718, compoundYield 98.3%

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

A solution of octyl amine (22.79 g, 176 mmol) and phenyl isocyanate (21 g, 176 mmol) in THF (200 ml) at 0° C. was stirred for 2 hours. The solvent was evaporated in vacuo and the residue was triturated with hexane to give 43 g of final product (173 mmol).

Workup

  1. customThe solvent was evaporated in vacuo
  2. customthe residue was triturated with hexane

Sources & evidence

ORD record
ord-60d621653d5746489f7203d49391a857
Source dataset
uspto-grants-2003_01
Patent number
US06506901B2

Reaction notes

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