Catechol → Guaiacol

HRID 1636095Notes

Reaction equation

HRID 1636095 reaction equation
[P].[C:2]1([C:4](=[CH:6][CH:7]=[CH:8][CH:9]=1)[OH:5])[OH:3].[CH3:10]O>>[C:4]1([O:5][CH3:10])[C:2](=[CH:9][CH:8]=[CH:7][CH:6]=1)[OH:3]

Participants

4

Reactant 3

HCID 289CatecholHCID 887MethanolHCID 5462309Phosphorus

Product 1

HCID 460Guaiacol

Conditions

Temperature
230 °C

Procedure

The mixed catechol-methyl alcohol vapor delivered from the evaporator was super heated to a temperature of 230° C. by a heat exchanger using a heating medium, mixed with a mixed gas separately prepared from a boron compound as a component of an etherification (dehydration reaction) catalyst and methyl alcohol, and then fed, as a material vapor, into a gas phase reactor packed with a phosphorus-containing etherification catalyst (as disclosed in Japanese Unexamined Patent Publication No. 4-341,345, Example 1). In the reactor, catechol catalytically reacted with methyl alcohol at a reaction temperature of 270° C. under a reaction pressure of 0.35 kg/cm2G, to produce guaiacol. The resultant guaiacol-containing gas was delivered from the reactor, and cooled and condensed by a cooler. The condensed liquid was collected from the cooler and stored in a storage tank.

Workup

  1. customThe mixed catechol-methyl alcohol vapor delivered from the evaporator
  2. additionmixed with a mixed gas
  3. customseparately prepared from a boron compound as a component of an etherification (dehydration reaction) catalyst and methyl alcohol
  4. additioncontaining etherification catalyst (

Sources & evidence

ORD record
ord-d2d65773df674d91bfddd515987be15f
Source dataset
uspto-grants-2003_01
Patent number
US06512147B2

Reaction notes

Loading…