Tetrahydrofuran → 1-(5-bromo-2-pyridinyl)-N-cyclopropylpyrrolidin-3-amine

HRID 163658Notes

Reaction equation

HRID 163658 reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]([N:8]2[CH2:9][CH:10]([O:13][S:14]([CH3:15])(=[O:16])=[O:17])[CH2:11][CH2:12]2)[n:6][cH:7]1.[CH2:22]1[O:23][CH2:24][CH2:25][CH2:26]1.[CH3:27][CH2:28][O:29][C:30]([CH3:31])=[O:32].[CH:18]1([NH2:21])[CH2:19][CH2:20]1>>[Br:1][c:2]1[cH:3][cH:4][c:5]([N:8]2[CH2:9][CH:10]([NH:21][CH:18]3[CH2:19][CH2:20]3)[CH2:11][CH2:12]2)[n:6][cH:7]1

Participants

5

Reactant 4

HCID 8028TetrahydrofuranHCID 8857Ethyl AcetateHCID 69828CyclopropylamineHCID 582694601-(5-Bromo-2-pyridinyl)-3-pyrrolidinyl methanesulfonate

Product 1

HCID 666731101-(5-bromo-2-pyridinyl)-N-cyclopropylpyrrolidin-3-amine

Sources & evidence

ORD record
ord-4986d480b5dd450aa8e65559ae963f70
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

Loading…