反应详情

A 30 mg portion of 5-chloro-2-(4-methyl-1-piperazinyl)benzoxazole was dissolved in 5 ml of DMF, and the solution which was stirred at room temperature was mixed with 100 mg of allyl iodide and then stirred for 12 hours. The solvent was evaporated under a reduced pressure, and the thus obtained mixture was purified by an LH-20 gel chromatography (chloroform:methanol=1:1) to obtain the title compound (36 mg) in light yellow color.

1. stirringstirred for 12 hours
2. customThe solvent was evaporated under a reduced pressure
3. customthe thus obtained mixture was purified by an LH-20 gel chromatography (chloroform:methanol=1:1)