HRID1637462

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID68424

Propanamide, 2-methyl-

C4H9NO

结构：CCCCC(CC(=O)Nc1cc(C(=O)O)ccc1C(C)(C)C)c1ccc(OC)cc1OC

HCID19348750

未命名化合物

PRODUCTS

生成物

HCID7914

Isopropyl ether

C6H14O

结构：CCCCC(CC(=O)Nc1cc(C(=O)NC(=O)C(C)C)ccc1C(C)(C)C)c1ccc(OC)cc1OC

HCID19348690

未命名化合物

PROCEDURE

实验过程

Following a similar procedure to that described in Example 139, but using 2-methylpropanamide and N-(2-t-butyl-5-carboxyphenyl)-3-(2,4-dimethoxyphenyl)heptanamide (prepared as described in Preparation 31B), the title compound was obtained as crystals, melting at 139-140° C. (from diisopropyl ether).

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-4a2ed6b94c9842d69d5b235abc161389
来源数据集: uspto-grants-2000_03
DOI: 10.6084/m9.figshare.5104873.v1
专利: US06040339
来源说明: uspto-grants-2000_03

反应 SMILES

[CH3:1][CH:2]([CH3:6])[C:3]([NH2:5])=[O:4].[C:7]([C:11]1[CH:16]=[CH:15][C:14]([C:17]([OH:19])=O)=[CH:13][C:12]=1[NH:20][C:21](=[O:38])[CH2:22][CH:23]([C:28]1[CH:33]=[CH:32][C:31]([O:34][CH3:35])=[CH:30][C:29]=1[O:36][CH3:37])[CH2:24][CH2:25][CH2:26][CH3:27])([CH3:10])([CH3:9])[CH3:8]>>[C:7]([C:11]1[CH:16]=[CH:15][C:14]([C:17]([NH:5][C:3](=[O:4])[CH:2]([CH3:6])[CH3:1])=[O:19])=[CH:13][C:12]=1[NH:20][C:21](=[O:38])[CH2:22][CH:23]([C:28]1[CH:33]=[CH:32][C:31]([O:34][CH3:35])=[CH:30][C:29]=1[O:36][CH3:37])[CH2:24][CH2:25][CH2:26][CH3:27])([CH3:8])([CH3:9])[CH3:10].[CH:31]([O:34][CH:2]([CH3:3])[CH3:6])([CH3:32])[CH3:30]