Dichloromethane → 4-(2-{4-[3-(tert-Butylamino-methyl)-phenyl]-pyrimidin-2-ylamino}-ethyl)-phenol
Reaction equation
[CH2:1]([O:2][C:3](=[O:4])[N:6]([CH2:7][c:8]1[cH:9][c:10](-[c:14]2[n:15][c:16]([NH:20][CH2:21][CH2:22][c:23]3[cH:24][cH:25][c:26]([OH:29])[cH:27][cH:28]3)[n:17][cH:18][cH:19]2)[cH:11][cH:12][cH:13]1)[C:30]([CH3:31])([CH3:32])[CH3:33])[CH:5]=[CH2:34].[CH2:55]([Cl:56])[Cl:57].[CH3:44][N:45]1[C:46](=[O:47])[CH2:48][C:49](=[O:50])[N:51]([CH3:52])[C:53]1=[O:54].[CH:35]([N:36]([CH:37]([CH3:38])[CH3:39])[CH2:40][CH3:41])([CH3:42])[CH3:43].[cH:58]1[cH:59][cH:60][c:61]([P:62]([Pd:63]([P:64]([c:65]2[cH:66][cH:67][cH:68][cH:69][cH:70]2)([c:71]2[cH:72][cH:73][cH:74][cH:75][cH:76]2)[c:77]2[cH:78][cH:79][cH:80][cH:81][cH:82]2)([P:83]([c:84]2[cH:85][cH:86][cH:87][cH:88][cH:89]2)([c:90]2[cH:91][cH:92][cH:93][cH:94][cH:95]2)[c:96]2[cH:97][cH:98][cH:99][cH:100][cH:101]2)[P:102]([c:103]2[cH:104][cH:105][cH:106][cH:107][cH:108]2)([c:109]2[cH:110][cH:111][cH:112][cH:113][cH:114]2)[c:115]2[cH:116][cH:117][cH:118][cH:119][cH:120]2)([c:121]2[cH:122][cH:123][cH:124][cH:125][cH:126]2)[c:127]2[cH:128][cH:129][cH:130][cH:131][cH:132]2)[cH:133][cH:134]1>>[NH:6]([CH2:7][c:8]1[cH:9][c:10](-[c:14]2[n:15][c:16]([NH:20][CH2:21][CH2:22][c:23]3[cH:24][cH:25][c:26]([OH:29])[cH:27][cH:28]3)[n:17][cH:18][cH:19]2)[cH:11][cH:12][cH:13]1)[C:30]([CH3:31])([CH3:32])[CH3:33]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-d86983e9812d4906bac6bb9ea9bd3756
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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