Phenacyl bromide → HCID 178418805, compound

HRID 1637934Notes

Reaction equation

HRID 1637934 reaction equation
[C:1]1([C:7]2[N:8]=[CH:9][NH:10][CH:11]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[N+:12]([O-])([O-:14])=[O:13].[NH4+].BrCC(C1C=CC=CC=1)=O>S(=O)(=O)(O)O.C(N)=O>[N+:12]([C:4]1[CH:3]=[CH:2][C:1]([C:7]2[N:8]=[CH:9][NH:10][CH:11]=2)=[CH:6][CH:5]=1)([O-:14])=[O:13]

Participants

6

Reactant 3

HCID 6259Phenacyl bromideHCID 22985Ammonium nitrateHCID 178418822HCID 178418822, compound

Product 1

HCID 178418805HCID 178418805, compound

Reagents, catalysts & solvents 2

HCID 713FormamideSolventHCID 1118Sulfuric AcidSolvent

Procedure

Prepared by nitrogenating 4-phenyl-imidazole in concentrated sulphuric acid with ammonium nitrate analogously to Example D (64% of theory; melting point: 220° C.) or by heating ω-bromo-acetophenone in formamide (160° C., 2.5 hours) (53% of theory; melting point: 220-222° C.).

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-feed8570c7314535b52b9c9ba847d846
Source dataset
uspto-grants-2000_03
Patent number
US06043254

Reaction notes

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