2-Bromopropiophenone → N-(4-METHYL-5-PHENYL-1H-IMIDAZOL-2-YL)ACETAMIDE

HRID 1637942Notes

Reaction equation

HRID 1637942 reaction equation
Br[CH:2]([CH3:11])[C:3]([C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][CH:6]=1)=O.[C:12]([NH:15][C:16]([NH2:18])=[NH:17])(=[O:14])[CH3:13]>CN(C=O)C>[C:12]([NH:15][C:16]1[NH:17][C:2]([CH3:11])=[C:3]([C:5]2[CH:10]=[CH:9][CH:8]=[CH:7][CH:6]=2)[N:18]=1)(=[O:14])[CH3:13]

Participants

4

Reactant 2

HCID 164522-BromopropiophenoneHCID 178475102HCID 178475102, compound

Product 1

HCID 9990847N-(4-METHYL-5-PHENYL-1H-IMIDAZOL-2-YL)ACETAMIDE

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

Prepared by reacting 2-bromo-propiophenone with 3 equivalents of 1-acetyl-guanidine in DMF (ambient temperature, 3 days).

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-d3db618a90a54f4da6af2f02394f0307
Source dataset
uspto-grants-2000_03
Patent number
US06043254

Reaction notes

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