huagongshe.com
HRID1637951

反应详情

EQUATION

反应方程式

HRID 1637951 的结构方程式

REACTANTS

反应物

4
结构：O=Cc1ccc([N+](=O)[O-])cc1
HCID541

4-Nitrobenzaldehyde

C7H5NO3

结构：O=C1CSC(=O)N1
HCID5437

Thiazolidinedione

C3H3NO2S

结构：C1CCNCC1
HCID8082

Piperidine

C5H11N

结构：O=C1NC(=O)C(=Cc2ccc([N+](=O)[O-])cc2)S1
HCID2768264

5-(4-nitrobenzylidene)-1,3-thiazolidine-2,4-dione

C10H6N2O4S

PRODUCTS

生成物

1
结构：Nc1ccc(C=C2SC(=O)NC2=O)cc1
HCID54182543

5-[(4-Aminophenyl)methylidene]-1,3-thiazolidine-2,4-dione

C10H8N2O2S

AUXILIARIES

试剂、催化剂与溶剂

3
结构：CC(=O)O
溶剂HCID176

Acetic Acid

C2H4O2

结构：O
溶剂HCID962

Water

H2O

结构：Cc1ccccc1
溶剂HCID1140

Toluene

C7H8

PROCEDURE

实验过程

Prepared by catalytic hydrogenation of 5-(4-nitro-benzylidene)-thiazolidin-2,4-dione [melting point: 265-270° C.; obtained by heating 4-nitro-benzaldehyde and 2 equivalents of thiazolidin-2,4-dione in the presence of piperidine in toluene using a water separator] in glacial acetic acid on palladium/charcoal (10%) (50° C., 3.5 bar, 0.5 hours).

WORKUP

后处理

  1. customobtained
  2. customon palladium/charcoal (10%) (50° C., 3.5 bar, 0.5 hours)