Potassium Carbonate → Methyl (o-nitrobenzylthio)-acetate

HRID 1638539Notes

Reaction equation

HRID 1638539 reaction equation
[N+:1]([C:4]1[CH:11]=[CH:10][CH:9]=[CH:8][C:5]=1[CH2:6]Cl)([O-:3])=[O:2].[SH:12][CH2:13][C:14]([O:16][CH3:17])=[O:15].C(=O)([O-])[O-].[K+].[K+]>CC(C)=O>[N+:1]([C:4]1[CH:11]=[CH:10][CH:9]=[CH:8][C:5]=1[CH2:6][S:12][CH2:13][C:14]([O:16][CH3:17])=[O:15])([O-:3])=[O:2]

Participants

5

Reactant 3

HCID 11430Potassium CarbonateHCID 119212-Nitrobenzyl chlorideHCID 16907Methyl Thioglycolate

Product 1

HCID 12136843Methyl (o-nitrobenzylthio)-acetate

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

A mixture of o-nitrobenzylchloride (17.2 g), methyl mercaptoacetate (8.9ml), and potassium carbonate (27.6 g) was refluxed with stirring in acetone (200 ml) for 6 hours. The reaction mixture was filtered and evaporated to leave the title compound as an oil.

Workup

  1. temperaturewas refluxed
  2. filtrationThe reaction mixture was filtered
  3. customevaporated

Sources & evidence

ORD record
ord-18339bb809024081b5f981240127d10d
Source dataset
uspto-grants-1989_11
Patent number
US04880799

Reaction notes

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