Succinimide → HCID 15696557, compound

HRID 1639044Notes

Reaction equation

HRID 1639044 reaction equation
[C:1]1(=[O:7])[NH:5][C:4](=[O:6])[CH2:3][CH2:2]1.[B].[H-].[Na+]>C(O)CCC>[CH2:1]([O:6][CH:4]1[NH:5][C:1](=[O:7])[CH2:2][CH2:3]1)[CH2:2][CH2:3][CH3:4]

Participants

5

Reactant 3

HCID 11439SuccinimideHCID 24758Sodium hydrideHCID 5462311Boron

Product 1

HCID 15696557HCID 15696557, compoundYield 66%

Reagents, catalysts & solvents 1

HCID 2631-ButanolSolvent2×

Procedure

The operation is done as for preparation 2, replacing the isopropanol by n-butanol and employing 14.32 g of succinimide in 600 cm3 of n-butanol and 8 g of boron and sodium hydride. 7.5 g of the expected product is obtained, m.p. 36°-38° C. The product can also be prepared by anodic alkylation according to a process described in Synthesis 4, 315-317 (1980).

Workup

  1. customThe operation is done as for preparation 2

Sources & evidence

ORD record
ord-f9749f3040fb4c8fa82f4ca0208a0db7
Source dataset
uspto-grants-1989_11
Patent number
US04882350

Reaction notes

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