反应详情

温度

60 °C

A mixture of 8 g of 5-hydroxy-pyrrolidin-2-one, 100 cm3 of n-heptanol and 4 g of Amberlite IR 120H is heated to 60° C. for 4 hours, filtered, then the solvent is eliminated under 0.3 mbar at 45° C./60° C. 11.9 g of the expected product is obtained, m.p. 52°-54° C., crystallized from hexane.

1. filtrationfiltered
2. customis eliminated under 0.3 mbar at 45° C.
3. custom60° C