Chlorodimethylsilane → [3-(4-Fluoro-3-phenoxyphenyl)propyl]dimethylchlorosilane

HRID 1639238Notes

Reaction equation

HRID 1639238 reaction equation
[F:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][CH:9]=[CH2:10])=[CH:4][C:3]=1[O:11][C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1.[CH3:18][SiH:19]([CH3:21])[Cl:20]>O1CCCC1>[F:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][CH2:9][CH2:10][Si:19]([CH3:21])([CH3:18])[Cl:20])=[CH:4][C:3]=1[O:11][C:12]1[CH:13]=[CH:14][CH:15]=[CH:16][CH:17]=1

Participants

4

Reactant 2

HCID 66108ChlorodimethylsilaneHCID 110751593-(4-Fluoro-3-phenoxyphenyl)-1-propene

Product 1

HCID 19838762[3-(4-Fluoro-3-phenoxyphenyl)propyl]dimethylchlorosilane

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

To a stirred mixture of 4.1 g (0.018 mole) of 3-(4-fluoro-3-phenoxyphenyl)-1-propene and 0.060 g (0.00015 mole) of hydrogen hexachloroplatinate hydrate in 15 mL of tetrahydrofuran was added slowly 2.0 g (0.021 mole) of dimethylchlorosilane. Upon completion of addition the reaction mixture was stirred overnight and then was used without further purification.

Workup

  1. additionUpon completion of addition the reaction mixture
  2. customwas used without further purification

Sources & evidence

ORD record
ord-078dd62b065f4b728382d3b0ce0e7ad8
Source dataset
uspto-grants-1989_11
Patent number
US04883789

Reaction notes

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