Triethylamine → HCID 23043803, compound

HRID 1639284Notes

Reaction equation

HRID 1639284 reaction equation
[CH3:1][S:2](Cl)(=[O:4])=[O:3].[NH2:6][C:7]1[CH:12]=[CH:11][C:10]([CH2:13][CH2:14][NH:15][C:16](=[O:46])[CH2:17][CH2:18][CH2:19][CH2:20][C:21]([NH:23][CH2:24][CH2:25][C:26]2[CH:31]=[CH:30][C:29]([O:32][CH3:33])=[C:28]([O:34][CH3:35])[C:27]=2[CH2:36][CH2:37][C:38]2[CH:43]=[CH:42][CH:41]=[C:40]([O:44][CH3:45])[CH:39]=2)=[O:22])=[CH:9][CH:8]=1.C(N(CC)CC)C>CN(C)C=O>[CH3:1][S:2]([NH:6][C:7]1[CH:12]=[CH:11][C:10]([CH2:13][CH2:14][NH:15][C:16](=[O:46])[CH2:17][CH2:18][CH2:19][CH2:20][C:21]([NH:23][CH2:24][CH2:25][C:26]2[CH:31]=[CH:30][C:29]([O:32][CH3:33])=[C:28]([O:34][CH3:35])[C:27]=2[CH2:36][CH2:37][C:38]2[CH:43]=[CH:42][CH:41]=[C:40]([O:44][CH3:45])[CH:39]=2)=[O:22])=[CH:9][CH:8]=1)(=[O:4])=[O:3]

Participants

5

Reactant 3

HCID 8471TriethylamineHCID 31297Methanesulfonyl chlorideHCID 23043978HCID 23043978, compound

Product 1

HCID 23043803HCID 23043803, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

Methanesulphonylchloride (0.41 ml) was added to a stirred solution of the Intermediate (a) (2.74 g) and triethylamine (0.74 ml) in dry dimethylformamide. The solution was stirred at room temperature for 10 hours.

Sources & evidence

ORD record
ord-1d9ecc66e88d4ee1b3e24d4802c91a04
Source dataset
uspto-grants-1989_11
Patent number
US04883804

Reaction notes

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