反应详情

温度

60 °C

To a suspension of lithium aluminum hydride (319 mg, 8.61 mmol) in tetrahydrofuran (17 mL) was added a solution of trans-2-(2-methyl-2H-indazol-4-yl)cyclopropanecarbaldehyde oxime (349 mg, 1.62 mmol) in tetrahydrofuran (17 mL) at room temperature, and the mixture was stirred at 60° C. for 1 hr. Sodium sulfate decahydrate (3.5 g) was added under ice-cooling, and the mixture was filtered through celite. The filtrate was concentrated under reduced pressure to give the title compound (325 mg, yield 99%).

1. temperaturecooling
2. filtrationthe mixture was filtered through celite
3. concentrationThe filtrate was concentrated under reduced pressure