反应详情

1.96 g (7.17 mmol) of 5-(2-fluoro-4-nitrophenoxy)-1H-indazole (from example IX) are dissolved in 50 ml of ethanol. 0.16 g (0.71 mmol) of platinum(IV) oxide are added, and the mixture is hydrogenated at room temperature under atmospheric pressure for two hours. For work-up, the mixture is filtered off with suction through kieselguhr, the filtercake is washed with ethanol and the filtrate is concentrated.

1. filtrationFor work-up, the mixture is filtered off with suction through kieselguhr
2. washthe filtercake is washed with ethanol
3. concentrationthe filtrate is concentrated