Dimethylformamide dimethyl acetal → HCID 76591494, compound

HRID 1640057Notes

Reaction equation

HRID 1640057 reaction equation
[CH3:1][NH:2][C:3](=[O:14])[C:4]1[CH:9]=[CH:8][C:7]([CH3:10])=[C:6]([N+:11]([O-:13])=[O:12])[CH:5]=1.CO[CH:17](OC)[N:18]([CH3:20])[CH3:19]>CN(C=O)C>[CH3:17][N:18]([CH3:20])[CH:19]=[CH:10][C:7]1[CH:8]=[CH:9][C:4]([C:3]([NH:2][CH3:1])=[O:14])=[CH:5][C:6]=1[N+:11]([O-:13])=[O:12]

Participants

4

Reactant 2

HCID 78373Dimethylformamide dimethyl acetalHCID 710838Benzamide, N,4-dimethyl-3-nitro-

Product 1

HCID 76591494HCID 76591494, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Conditions

Temperature
80 °C

Procedure

1.65 g (8.49 mmol) of N-methyl-4-methyl-3-nitrobenzamide was dissolved into 9.9 mL of DMF and 6.49 g (50.90 mmol) of N,N-dimethylformamide dimethylacetal was added dropwise to this solution under a nitrogen atmosphere at room temperature, and the reaction mixture was heated and stirred at 80° C. for 46 hours.

Workup

  1. additionwas added dropwise to this solution under a nitrogen atmosphere at room temperature
  2. temperaturethe reaction mixture was heated

Sources & evidence

ORD record
ord-7620393f8c254e06875dc0596b08a10f
Source dataset
uspto-grants-2012_02
Patent number
US08110688B2

Reaction notes

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