Hydrochloric Acid → N-(cis-4-Acetylamino-cyclohexyl)-5-fluoro-2-(3-methylsulfanyl-phenoxy)-nicotinamide
Reaction equation
[CH3:28][CH2:29][N:30]([CH2:31][CH3:32])[CH2:33][CH3:34].[CH3:35][C:36]([Cl:37])=[O:38].[Cl:39][CH2:40][Cl:41].[ClH:1].[NH2:2][CH:3]1[CH2:4][CH2:5][CH:6]([NH:9][C:10]([c:11]2[c:12]([O:18][c:19]3[cH:20][c:21]([S:25][CH3:26])[cH:22][cH:23][cH:24]3)[n:13][cH:14][c:15]([F:17])[cH:16]2)=[O:27])[CH2:7][CH2:8]1>>[NH:2]([CH:3]1[CH2:4][CH2:5][CH:6]([NH:9][C:10]([c:11]2[c:12]([O:18][c:19]3[cH:20][c:21]([S:25][CH3:26])[cH:22][cH:23][cH:24]3)[n:13][cH:14][c:15]([F:17])[cH:16]2)=[O:27])[CH2:7][CH2:8]1)[C:36]([CH3:35])=[O:38]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-e2a72909414b462f8b1699d80150c8dd
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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