反应详情

6.0 g (36 mmol) methylene-(2-methyl-2-thiophene-3-yl-propyl)-amine, 11 mL (45 mmol) 4M HCl and 12 mL (0.14 mol) conc. HCl were stirred at RT over the weekend. The reaction mixture was made alkaline with a 4M sodium hydroxide solution. The precipitate formed was suction filtered, washed with water and dried. The substance was purified on Alox. The product-containing fractions were combined and concentrated to dryness by rotary evaporation.

1. customThe precipitate formed
2. filtrationfiltered
3. washwashed with water
4. customdried
5. customThe substance was purified on Alox
6. concentrationconcentrated to dryness by rotary evaporation