Pyrazole → 1-(4-Methoxyphenyl)-1H-pyrazole

HRID 1641424Notes

Reaction equation

HRID 1641424 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6](B(O)O)=[CH:5][CH:4]=1.[NH:12]1[CH:16]=[CH:15][CH:14]=[N:13]1>>[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([N:12]2[CH:16]=[CH:15][CH:14]=[N:13]2)=[CH:5][CH:4]=1

Participants

3

Reactant 2

HCID 1048PyrazoleHCID 201262(4-Methoxyphenyl)boronic acid

Product 1

HCID 122381311-(4-Methoxyphenyl)-1H-pyrazoleYield 40%

Procedure

The title compound was prepared from 4-methoxyphenylboronic acid (0.45 g, 2.94 mmol), pyrazole (0.4 g, 1.47 mmol) using the general procedure A with a yield of 40% (0.4 g); MS (APCI) m/z: 203 (M+1, 100).

Sources & evidence

ORD record
ord-81e85c9a8ac247ba99c09b842ca68db7
Source dataset
uspto-grants-2012_02
Patent number
US08115005B2

Reaction notes

Loading…