Water → HCID 25026399, compound

HRID 1641607Notes

Reaction equation

HRID 1641607 reaction equation
[OH:1][C:2]1[CH:7]=[CH:6][C:5]([CH:8]=[CH:9][C:10]([C:12]2[CH:17]=[CH:16][C:15]([OH:18])=[CH:14][CH:13]=2)=[O:11])=[CH:4][C:3]=1[O:19][CH3:20].O>O1CCCC1.[Pd]>[OH:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][CH2:9][C:10]([C:12]2[CH:17]=[CH:16][C:15]([OH:18])=[CH:14][CH:13]=2)=[O:11])=[CH:4][C:3]=1[O:19][CH3:20]

Participants

5

Reactant 2

HCID 962WaterHCID 667388783-(4-Hydroxy-3-methoxyphenyl)-1-(4-hydroxyphenyl)prop-2-en-1-one

Product 1

HCID 25026399HCID 25026399, compoundYield 89.3%

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalyst2×HCID 8028TetrahydrofuranSolvent

Procedure

10 g of 3-(4-hydroxy-3-methoxyphenyl)-1-(4-hydroxyphenyl)-2-propen-1-one are dissolved in 100 g of tetrahydrofuran, combined with 0.2 g of Pd on activated carbon (Pd content: 5 wt. %, water content approx. 50 wt. %, in each case relative to the total mass of the catalyst) and hydrogenated at standard pressure and room temperature (approx. 20° C.) After removal of the catalyst and the solvent, 9 g of 3-(4-hydroxy-3-methoxyphenyl)-1-(4-hydroxyphenyl)-propan-1-one are obtained. Yield: 89% of theoretical

Workup

  1. customhydrogenated at standard pressure and room temperature (approx. 20° C.)
  2. customAfter removal of the catalyst

Sources & evidence

ORD record
ord-ae5bc0505173444580c022b88680ded2
Source dataset
uspto-grants-2012_02
Patent number
US08115033B2

Reaction notes

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