Trifluoroacetic acid → Trifluoroacetate

HRID 1642058Notes

Reaction equation

HRID 1642058 reaction equation
[CH2:1]([O:3][C:4](=[O:24])[CH2:5][N:6]([C:15]1[CH:20]=[CH:19][CH:18]=[C:17]([N+:21]([O-:23])=[O:22])[CH:16]=1)[S:7]([NH:10]C(C)(C)C)(=[O:9])=[O:8])[CH3:2].[C:25]([OH:31])([C:27]([F:30])([F:29])[F:28])=[O:26]>O1CCOCC1>[CH2:1]([O:3][C:4](=[O:24])[CH2:5][N:6]([C:15]1[CH:20]=[CH:19][CH:18]=[C:17]([N+:21]([O-:23])=[O:22])[CH:16]=1)[S:7]([NH2:10])(=[O:9])=[O:8])[CH3:2].[F:28][C:27]([F:30])([F:29])[C:25]([O-:31])=[O:26]

Participants

5

Reactant 2

HCID 6422Trifluoroacetic acidHCID 66755636HCID 66755636, compound

Product 2

HCID 84468TrifluoroacetateHCID 66755370(3-Nitro-phenyl-N-(aminosulfonyl)amino)-acetic acid ethyl ester

Reagents, catalysts & solvents 1

HCID 312751,4-DioxaneSolvent

Procedure

5 mmol of (3-nitro-phenyl-N-(t-butylaminosulfonyl)amino)-acetic acid ethyl ester is dissolved in 20 ml of 90% aqueous TFA and the mixture obtained is stirred for 1 hour at rt. The mixture obtained is diluted with dioxane and solvent is evaporated. (3-Nitro-phenyl-N-(aminosulfonyl)amino)-acetic acid ethyl ester in the form of a trifluoroacetate is obtained.

Workup

  1. customthe mixture obtained
  2. customThe mixture obtained
  3. customis evaporated

Sources & evidence

ORD record
ord-33cc340f28a9432b8d1dfeb5c7afd54e
Source dataset
uspto-grants-2012_02
Patent number
US08119617B2

Reaction notes

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