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HRID1642092

反应详情

EQUATION

反应方程式

HRID 1642092 的结构方程式

REACTANTS

反应物

3
结构：O=[N+]([O-])O
HCID944

Nitric Acid

HNO3

结构：O=C([O-])O.[Na+]
HCID516892

Sodium Bicarbonate

CHNaO3

结构：c1cnc2[nH]ccc2n1
HCID5370803

5H-Pyrrolo[2,3-b]pyrazine

C6H5N3

PRODUCTS

生成物

1
结构：O=[N+]([O-])c1c[nH]c2nccnc12
HCID12207192

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：O
溶剂HCID962

Water

H2O

CONDITIONS

反应条件

温度
0 °C

PROCEDURE

实验过程

7-Nitro-5H-pyrrolo[2,3-b]pyrazine (5) is prepared by adding 5H-pyrrolo[2,3-b]pyrazine (3) to fuming nitric acid while cooling (e.g. 0° C.). After stirring for one to several hours, water is carefully added and the mixture neutralized with saturated sodium bicarbonate. The solids are collected by filtration and dried to provide 7-nitro-5H-pyrrolo[2,3-b]pyrazine 5.

WORKUP

后处理

  1. custom7-Nitro-5H-pyrrolo[2,3-b]pyrazine (5) is prepared
  2. additionis carefully added
  3. filtrationThe solids are collected by filtration
  4. customdried