Benzoylhydrazine → N-[(E)-[(E)-3-phenylprop-2-enylidene]amino]benzamide

HRID 1644166Notes

Reaction equation

HRID 1644166 reaction equation
[C:1]([NH:9][NH2:10])(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH:11]1[CH:16]=[CH:15][C:14](/[CH:17]=[CH:18]/[CH:19]=O)=[CH:13][CH:12]=1>CCCCCC>[C:14]1(/[CH:17]=[CH:18]/[CH:19]=[N:10]/[NH:9][C:1](=[O:8])[C:2]2[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=2)[CH:15]=[CH:16][CH:11]=[CH:12][CH:13]=1

Participants

4

Reactant 2

HCID 11955BenzoylhydrazineHCID 637511Cinnamaldehyde

Product 1

HCID 6870846N-[(E)-[(E)-3-phenylprop-2-enylidene]amino]benzamideYield 90%

Reagents, catalysts & solvents 1

HCID 8058HexaneSolvent

Procedure

A mixture of 1a (3.00 g, 22.0 mmol) and trans cinnamic aldehyde (4.35 g, 32.9 mmol, origin: Aldrich) in hexane (100 ml) was stirred at room temperature for 2 h. The reaction mixture was filtered, the residue washed with hexane and dried under vacuum to give 4.95 g (90%) of a white solid.

Workup

  1. filtrationThe reaction mixture was filtered
  2. washthe residue washed with hexane
  3. customdried under vacuum

Sources & evidence

ORD record
ord-68e97b156d944ea29316e7a2c7a8d981
Source dataset
uspto-grants-2012_02
Patent number
US08124578B2

Reaction notes

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