m-Chloroperbenzoic acid → HCID 178458532, compound

HRID 1644589Notes

Reaction equation

HRID 1644589 reaction equation
[CH2:1]([O:8][C:9]1[CH:10]=[CH:11][C:12]([O:24][CH:25]([CH3:27])[CH3:26])=[C:13]([C:15]2[NH:23][C:18]3=[N:19][CH:20]=[CH:21][CH:22]=[C:17]3[N:16]=2)[CH:14]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.ClC1C=CC=C(C(OO)=[O:36])C=1>C(Cl)(Cl)Cl>[CH2:1]([O:8][C:9]1[CH:10]=[CH:11][C:12]([O:24][CH:25]([CH3:27])[CH3:26])=[C:13]([C:15]2[NH:23][C:18]3=[N+:19]([O-:36])[CH:20]=[CH:21][CH:22]=[C:17]3[N:16]=2)[CH:14]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

4

Reactant 2

HCID 70297m-Chloroperbenzoic acidHCID 178458530HCID 178458530, compound

Product 1

HCID 178458532HCID 178458532, compound

Reagents, catalysts & solvents 1

HCID 6212ChloroformSolvent

Procedure

A solution (10 ml) of 2-[5-(benzyloxy)-2-isopropoxyphenyl]-3H-imidazo[4,5-b]pyridine (0.2 g) and m-chloroperbenzoic acid (0.15 g) in chloroform was stirred at room temperature for 18 hr. The reaction mixture was washed with aqueous sodium hydrogencarbonate solution, dried over magnesium sulfate and concentrated to give the title compound as colorless crystals. purity 80%. M+H: 376.

Workup

  1. washThe reaction mixture was washed with aqueous sodium hydrogencarbonate solution
  2. dry with materialdried over magnesium sulfate
  3. concentrationconcentrated

Sources & evidence

ORD record
ord-aa724118d7ce49c9958965d8bf093f64
Source dataset
uspto-grants-2012_02
Patent number
US08124617B2

Reaction notes

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