Dichloromethane → 2,6-dichloro-N-(tetrahydro-2H-pyran-4-yl)nicotinamide
Reaction equation
[CH2:19]([N:20]([CH:21]([CH3:22])[CH3:23])[CH:24]([CH3:25])[CH3:26])[CH3:27].[Cl:1][c:2]1[c:3]([C:4](=[O:5])[Cl:6])[cH:7][cH:8][c:9]([Cl:11])[n:10]1.[Cl:28][CH2:29][Cl:30].[NH2:12][CH:13]1[CH2:14][CH2:15][O:16][CH2:17][CH2:18]1>>[Cl:1][c:2]1[c:3]([C:4](=[O:5])[NH:12][CH:13]2[CH2:14][CH2:15][O:16][CH2:17][CH2:18]2)[cH:7][cH:8][c:9]([Cl:11])[n:10]1Participants
5
Sources & evidence
- ORD record
- ord-a90f2c93b151482daf423c5d8bfa0d54
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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