m-Chloroperbenzoic acid → HCID 73071643, compound

HRID 1645379Notes

Reaction equation

HRID 1645379 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]2[C:9](=[CH:10][C:11]=1[O:12][CH3:13])[C:8](=[O:14])[C:7](=[CH:15][C:16]1[CH:21]=[CH:20][N:19]=[CH:18][CH:17]=1)[CH2:6]2.ClC1C=CC=C(C(OO)=[O:30])C=1.C(=O)(O)[O-].[Na+]>C(Cl)Cl>[CH3:1][O:2][C:3]1[CH:4]=[C:5]2[C:9](=[CH:10][C:11]=1[O:12][CH3:13])[C:8](=[O:14])[C:7](=[CH:15][C:16]1[CH:21]=[CH:20][N+:19]([O-:30])=[CH:18][CH:17]=1)[CH2:6]2

Participants

5

Reactant 3

HCID 70297m-Chloroperbenzoic acidHCID 516892Sodium BicarbonateHCID 533951325,6-Dimethoxy-2-(4-pyridyl)methylene-1-indanone

Product 1

HCID 73071643HCID 73071643, compoundYield 94.6%

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

4-[(5,6-Dimethoxy-1-indanon-2-ylidene)methyl]pyridine (2.5 g) was dissolved in methylene chloride (60 ml) and chilled. m-Chloroperbenzoic acid (2.0 g) was added to reaction mixture and then stirred for 4 hours. Solid obtained was filtered. The wet solid so obtained was stirred with 10% sodium bicarbonate solution. The solid was filtered, washed with acetone and then dried to get the title compound (2.5 g).

Workup

  1. temperaturechilled
  2. customSolid obtained
  3. filtrationwas filtered
  4. customThe wet solid so obtained
  5. filtrationThe solid was filtered
  6. washwashed with acetone
  7. customdried

Sources & evidence

ORD record
ord-d39939978e6c49ec94330e8c8a21cb34
Source dataset
uspto-grants-2012_02
Patent number
US08124783B2

Reaction notes

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