Benzyl Chloride → HCID 86632336, compound

HRID 1645410Notes

Reaction equation

HRID 1645410 reaction equation
[CH2:1]1[S:9](=[O:11])(=[O:10])[O:8][CH2:7][CH2:6][O:5][S:2]1(=[O:4])=[O:3].[H-].[Na+].[CH2:14](Cl)[C:15]1[CH:20]=[CH:19]C=[CH:17][CH:16]=1>C(COC)OC.[OH-].[Na+]>[CH2:1]([S:9]([OH:8])(=[O:11])=[O:10])[S:2]([O:5][CH2:6][C:7]1[CH:19]=[CH:20][CH:15]=[CH:16][CH:17]=1)(=[O:4])=[O:3].[CH2:14]=[CH2:15]

Participants

6

Reactant 3

HCID 7503Benzyl ChlorideHCID 24758Sodium hydrideHCID 57513Cyclodisone

Product 1

HCID 86632336HCID 86632336, compoundYield 34.7%

Reagents, catalysts & solvents 2

HCID 80711,2-DimethoxyethaneSolvent2×HCID 14798Sodium HydroxideSolvent

Procedure

To a solution of 2.6 g of ethylene methanedisulfonate in 50 mL of glyme and 1.0 g of NaH was added 3 g of benzyl chloride. After rotoevaporation of the glyme the residue was taken up in 25 mL of 0.5 M NaOH, filtered, and acidified to give 1.21 g of ethylene benzyl methanedisulfonate, m.p. 170-174° C. (90-3).

Workup

  1. filtrationfiltered

Sources & evidence

ORD record
ord-0eedd579fd3946a8ac960fffda874f49
Source dataset
uspto-grants-2012_02
Patent number
US08124793B2

Reaction notes

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