Ethyl ketone → (2,2-Diethyl-1,3-dioxan-5-yl)methanol

HRID 1645573Notes

Reaction equation

HRID 1645573 reaction equation
[OH:1][CH2:2][CH:3]([CH2:6][OH:7])[CH2:4][OH:5].[CH3:8][CH2:9][C:10](=O)[CH2:11][CH3:12]>>[CH2:9]([C:10]1([CH2:11][CH3:12])[O:5][CH2:4][CH:3]([CH2:6][OH:7])[CH2:2][O:1]1)[CH3:8]

Participants

3

Reactant 2

HCID 7288Ethyl ketoneHCID 78432Trimethylolmethane

Product 1

HCID 14629254(2,2-Diethyl-1,3-dioxan-5-yl)methanolYield 46%

Procedure

The same procedure as in the step (7a) of Example 7 was repeated using 2-(hydroxymethyl)-1,3-propanediol, and 3-pentanone to obtain the title compound (1.5 g, yield: 46%) as a light yellow oil.

Sources & evidence

ORD record
ord-295a813ba4fb4d6fb0367b372dcc9cde
Source dataset
uspto-grants-2012_02
Patent number
US08124780B2

Reaction notes

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