Potassium Acetate → HCID 19801701, compound

HRID 1646166Notes

Reaction equation

HRID 1646166 reaction equation
[CH3:1][N:2]1[C:6]2[CH:7]=[CH:8][C:9]([C:11](=[O:15])[CH2:12][CH2:13]Cl)=[CH:10][C:5]=2[O:4][C:3]1=[O:16].C([O-])(=O)C.[K+]>CN(C)C=O>[CH3:1][N:2]1[C:6]2[CH:7]=[CH:8][C:9]([C:11](=[O:15])[CH:12]=[CH2:13])=[CH:10][C:5]=2[O:4][C:3]1=[O:16]

Participants

4

Reactant 2

HCID 517044Potassium AcetateHCID 14751603HCID 14751603, compound

Product 1

HCID 19801701HCID 19801701, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

In a 150-ml ground-necked flask equipped with a reflux condenser, 5 g (0.02 mol) of 3-methyl-6-( 3-chloropropionyl)benzoxazolinone, described in Patent Application FR 89/02554, are dissolved in 70 ml of dimethylformamide. 2.04 g of potassium acetate are introduced. The mixture is heated with magnetic stirring to 75°-80° C. for 50 min. After cooling, the reaction mixture is poured into ice-cold water. The resulting mixture is stirred for 0.5 h. The precipitate obtained is drained, washed with water, dried and recrystallized in toluene.

Workup

  1. customIn a 150-ml ground-necked flask equipped with a reflux condenser
  2. temperatureThe mixture is heated
  3. temperatureAfter cooling
  4. additionthe reaction mixture is poured into ice-cold water
  5. stirringThe resulting mixture is stirred for 0.5 h
  6. customThe precipitate obtained
  7. washwashed with water
  8. customdried
  9. customrecrystallized in toluene

Sources & evidence

ORD record
ord-36621d099e724b5799c10a8d1e740c48
Source dataset
uspto-grants-1993_01
Patent number
US05179091

Reaction notes

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