反应详情

West German Patent No. 1,240,854 discloses a method for synthesizing 3-cyano-3,5,5-trimethyl cyclohexanone by causing isophorone to react with hydrogen cyanide in the presence of an alkali metal salt as a catalyst with methanol used as a dispersant for the catalyst. When this method was replicated, however, it was found that the reaction produced 3-cyano-3,5,5-trimethyl cyclohexane only in a low yield of about 70% and entailed by-production of a large amount of polymer of hydrogen cyanide. Thus, this method is problematic as a commercial process.