Hydrogen Bromide → HCID 19921723, compound

HRID 1647099Notes

Reaction equation

HRID 1647099 reaction equation
[I-].[C:2]1([CH:8]([N+:10]2[CH:15]=[CH:14][CH:13]=[CH:12][C:11]=2[CH:16]2OCCO2)[CH3:9])[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[BrH:21]>>[Br-:21].[CH3:9][C:8]1[N+:10]2[CH:15]=[CH:14][CH:13]=[CH:12][C:11]=2[CH:16]=[C:7]2[CH:6]=[CH:5][CH:4]=[CH:3][C:2]=12

Participants

3

Reactant 2

HCID 260Hydrogen BromideHCID 19921725HCID 19921725, compound

Product 1

HCID 19921723HCID 19921723, compoundYield 76%

Procedure

A mixture of 1-(1-phenylethyl)-2-(1,3-dioxolan-2-yl)pyridinium iodide (3.5 g, 9 mmol) and 48% hydrobromic acid (20 mL) was refluxed for 16 hours. The solvent was removed in vacuo to afford 1.9 g (76%) of 6-methylbenzo[b]quinolizinium bromide (Formula VII: R2 =H;R1 =CH3 ; Z- =Br-).

Workup

  1. temperaturewas refluxed for 16 hours
  2. customThe solvent was removed in vacuo

Sources & evidence

ORD record
ord-dc50a3cccbdb42529b1511bc2105d15e
Source dataset
uspto-grants-1995_07
Patent number
US05430036

Reaction notes

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