反应详情

温度

70 °C

A mixture of 2.61 g of 5-[3-(methylamino)propylidene]-5H-dibenzo[a,d]cycloheptene, 2.00 g of ethyl bromoacetate, 1.38 g of potassium carbonate, and 13 ml of N,N-dimethylformamide was stirred at 70° C. for 4 hours. After the reaction was completed, water was added to the reaction mixture and the mixture was then extracted with diethyl ether. The ether layer was washed with water and dried, and then the solvent was removed by distillation. The residue was purified by column chromatography on aluminum oxide [n-hexane-diethyl ether (1:1)] to give 1.88 g of slightly yellow viscous liquid.

1. extractionthe mixture was then extracted with diethyl ether
2. washThe ether layer was washed with water
3. customdried
4. customthe solvent was removed by distillation
5. customThe residue was purified by column chromatography on aluminum oxide [n-hexane-diethyl ether (1:1)]
6. customto give 1.88 g of slightly yellow viscous liquid