Potassium Chloride → Citrate

HRID 1647512Notes

Reaction equation

HRID 1647512 reaction equation
[Cl-].[K+].[C:3]([O-:15])(=[O:14])[CH2:4][C:5]([CH2:10][C:11]([O-:13])=[O:12])([C:7]([O-:9])=[O:8])[OH:6].[K+].[K+].[K+].C([O-])(=O)CC(CC([O-])=O)(C([O-])=O)O.[Mg+2:32].C([O-])(=O)CC(CC([O-])=O)(C([O-])=O)O.[Mg+2].[Mg+2].C([O-])(=O)CC(CC([O-])=O)(C([O-])=O)O.[Mg+2].[K+]>>[Mg:32].[C:3]([O-:15])(=[O:14])[CH2:4][C:5]([CH2:10][C:11]([O-:13])=[O:12])([C:7]([O-:9])=[O:8])[OH:6]

Participants

6

Reactant 4

HCID 4873Potassium Chloride2×HCID 13344Tripotassium citrateHCID 6099959Trimagnesium dicitrateHCID 21986909Potassium-magnesium citrate2×

Product 2

HCID 31348CitrateHCID 5462224Magnesium

Procedure

Each patient underwent five phases of study: placebo, potassium chloride, potassium citrate, magnesium citrate, and potassium-magnesium citrate. The results (mean values for the two patients) are outlined in Table 1. Compared to potassium chloride, potassium magnesium citrate gave a higher urinary pH, magnesium, and citrate. Compared to potassium citrate, potassium magnesium citrate produced a greater citrate excretion as well as enhanced magnesium excretion. Compared to magnesium citrate, potassium magnesium citrate gave higher values for urinary pH and citrate. Finally, compared to the placebo, potassium magnesium citrate produced higher values for urinary pH, magnesium, potassium and citrate, and lower values for urinary calcium and oxalate.

Workup

  1. customThe results (mean values for the two patients)

Sources & evidence

ORD record
ord-31f911edfb6a49f8bc44739dc4238953
Source dataset
uspto-grants-1995_07
Patent number
US05432200

Reaction notes

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