O-Xylene → HCID 15376513, compound

HRID 1648192Notes

Reaction equation

HRID 1648192 reaction equation
[C:1]1([C:7]2[C:8](=O)[O:9][C:10](C)(C)[O:11][CH:12]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.C=[N:17][C:18]([CH3:26])([C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1)[CH3:19].[C:27]1(C)C(C)=CC=CC=1>>[CH3:27][C:8]1[O:9][CH2:10][N:17]([C:18]([CH3:26])([C:20]2[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=2)[CH3:19])[C:12](=[O:11])[C:7]=1[C:1]1[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

Participants

4

Reactant 3

HCID 7237O-XyleneHCID 131570332,2-Dimethyl-5-phenyl-2H,4H-1,3-dioxin-4-oneHCID 15405502HCID 15405502, compound

Product 1

HCID 15376513HCID 15376513, compound

Procedure

Xylene (2 ml) was added to a mixture of 5-phenyl-2,2-dimethyl-2H,4H-1,3-dioxin-4-one (0.82 g) and N-methylene-1-methyl-1-phenylethylamine (0.59 g), and the resulting mixture was heated at reflux for 20 minutes for reaction. The reaction mixture was purified by silica gel chromatography to obtain the captioned compound (0.9 g).

Workup

  1. temperaturethe resulting mixture was heated
  2. temperatureat reflux for 20 minutes for reaction
  3. customThe reaction mixture was purified by silica gel chromatography

Sources & evidence

ORD record
ord-cba4ffcbabdc4382a3078b687bc90027
Source dataset
uspto-grants-1995_07
Patent number
US05436224

Reaction notes

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