Nitroethane → 1-(2-Chlorophenyl)propan-2-one

HRID 1648226Notes

Reaction equation

[Cl:1][C:2]1[CH:9]=[CH:8][CH:7]=[CH:6][C:3]=1[CH:4]=O.[N+](CC)([O-])=O.FC1C=CC=C[C:17]=1[CH:18]=[O:19].[N+](CCC)([O-])=O>>[Cl:1][C:2]1[CH:9]=[CH:8][CH:7]=[CH:6][C:3]=1[CH2:4][C:18](=[O:19])[CH3:17]

Participants

Reactant 4

HCID 6587Nitroethane

HCID 69962-Chlorobenzaldehyde

HCID 79031-Nitropropane

HCID 67970o-Fluorobenzaldehyde

Product 1

HCID 2293551-(2-Chlorophenyl)propan-2-oneYield 27%

Procedure

Following a procedure similar to that described in Preparation 9, except that equivalent amounts of 2-chlorobenzaldehyde and nitroethane were used in place of the 2-fluorobenzaldehyde and nitropropane, the title compound was obtained as a brown oil in a yield of 27%.

Sources & evidence

ORD record: ord-763ad439ed994213986cb28707062df0
Source dataset: uspto-grants-1995_07
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05436242

Reaction notes

Loading…